Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Vav guanine nucleotide exchange factor 3. (782 aa)    
Predicted Functional Partners:
LCP2
Lymphocyte cytosolic protein 2.
   
 0.990
SYK
Tyrosine-protein kinase.
   
 0.988
VAV1
Vav guanine nucleotide exchange factor 1.
  
 
 
0.982
RHOA
Ras homolog family member A.
    
 0.974
ZAP70
Tyrosine-protein kinase.
   
 0.973
CDC42
Cell division cycle 42.
   
 0.973
ENSCSAP00000002624
Uncharacterized protein.
   
 0.971
ENSCSAP00000002631
Ig-like domain-containing protein.
   
 0.971
RAC2
Rac family small GTPase 2.
   
 0.965
RAC1
Rac family small GTPase 1.
   
 0.964
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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