| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATR | BLM | ENSCSAP00000007482 | ENSCSAP00000013082 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | BLM RecQ like helicase. | 0.896 |
| ATR | FANCM | ENSCSAP00000007482 | ENSCSAP00000011403 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | FA complementation group M. | 0.991 |
| ATR | MLH1 | ENSCSAP00000007482 | ENSCSAP00000010283 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | MutL homolog 1. | 0.486 |
| ATR | MSH4 | ENSCSAP00000007482 | ENSCSAP00000016626 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | MutS homolog 4. | 0.762 |
| ATR | MSH5 | ENSCSAP00000007482 | ENSCSAP00000004953 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.511 |
| ATR | PMS2 | ENSCSAP00000007482 | ENSCSAP00000013765 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | PMS1 homolog 2, mismatch repair system component. | 0.509 |
| ATR | RAD51 | ENSCSAP00000007482 | ENSCSAP00000003814 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.921 |
| ATR | TOP3A | ENSCSAP00000007482 | ENSCSAP00000004318 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.750 |
| BLM | ATR | ENSCSAP00000013082 | ENSCSAP00000007482 | BLM RecQ like helicase. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.896 |
| BLM | FANCM | ENSCSAP00000013082 | ENSCSAP00000011403 | BLM RecQ like helicase. | FA complementation group M. | 0.996 |
| BLM | MLH1 | ENSCSAP00000013082 | ENSCSAP00000010283 | BLM RecQ like helicase. | MutL homolog 1. | 0.961 |
| BLM | MLH3 | ENSCSAP00000013082 | ENSCSAP00000008369 | BLM RecQ like helicase. | MutL homolog 3. | 0.705 |
| BLM | MSH4 | ENSCSAP00000013082 | ENSCSAP00000016626 | BLM RecQ like helicase. | MutS homolog 4. | 0.773 |
| BLM | MSH5 | ENSCSAP00000013082 | ENSCSAP00000004953 | BLM RecQ like helicase. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.770 |
| BLM | PMS1 | ENSCSAP00000013082 | ENSCSAP00000008492 | BLM RecQ like helicase. | PMS1 homolog 1, mismatch repair system component. | 0.411 |
| BLM | PMS2 | ENSCSAP00000013082 | ENSCSAP00000013765 | BLM RecQ like helicase. | PMS1 homolog 2, mismatch repair system component. | 0.445 |
| BLM | RAD51 | ENSCSAP00000013082 | ENSCSAP00000003814 | BLM RecQ like helicase. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.986 |
| BLM | TOP3A | ENSCSAP00000013082 | ENSCSAP00000004318 | BLM RecQ like helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.999 |
| FANCM | ATR | ENSCSAP00000011403 | ENSCSAP00000007482 | FA complementation group M. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.991 |
| FANCM | BLM | ENSCSAP00000011403 | ENSCSAP00000013082 | FA complementation group M. | BLM RecQ like helicase. | 0.996 |
