GNG12 protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GNG12

Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)

Predicted Functional Partners:

GNB3

0.977

GNB2

0.962

GNA12

0.960

GNAO1

0.953

KCNJ6

0.937

ADCY5

0.936

ADCYAP1R1

0.933

PAK1

0.931

PAK3

0.931

DRD3

0.927

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNAO1	ENSCSAP00000003847	ENSCSAP00000001466	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha o1.	0.950
ADCY5	GNB2	ENSCSAP00000003847	ENSCSAP00000013954	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit beta 2.	0.933
ADCY5	GNB3	ENSCSAP00000003847	ENSCSAP00000006464	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit beta 3.	0.935
ADCY5	GNG12	ENSCSAP00000003847	ENSCSAP00000016650	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCYAP1R1	GNB2	ENSCSAP00000010897	ENSCSAP00000013954	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 2.	0.943
ADCYAP1R1	GNB3	ENSCSAP00000010897	ENSCSAP00000006464	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.934
ADCYAP1R1	GNG12	ENSCSAP00000010897	ENSCSAP00000016650	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.933
DRD3	GNAO1	ENSCSAP00000003202	ENSCSAP00000001466	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha o1.	0.961
DRD3	GNB2	ENSCSAP00000003202	ENSCSAP00000013954	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.956
DRD3	GNB3	ENSCSAP00000003202	ENSCSAP00000006464	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.950
DRD3	GNG12	ENSCSAP00000003202	ENSCSAP00000016650	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.927
GNA12	GNB2	ENSCSAP00000013650	ENSCSAP00000013954	G protein subunit alpha 12.	G protein subunit beta 2.	0.734
GNA12	GNB3	ENSCSAP00000013650	ENSCSAP00000006464	G protein subunit alpha 12.	G protein subunit beta 3.	0.716
GNA12	GNG12	ENSCSAP00000013650	ENSCSAP00000016650	G protein subunit alpha 12.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.960
GNAO1	ADCY5	ENSCSAP00000001466	ENSCSAP00000003847	G protein subunit alpha o1.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.950
GNAO1	DRD3	ENSCSAP00000001466	ENSCSAP00000003202	G protein subunit alpha o1.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.961
GNAO1	GNB2	ENSCSAP00000001466	ENSCSAP00000013954	G protein subunit alpha o1.	G protein subunit beta 2.	0.975
GNAO1	GNB3	ENSCSAP00000001466	ENSCSAP00000006464	G protein subunit alpha o1.	G protein subunit beta 3.	0.976
GNAO1	GNG12	ENSCSAP00000001466	ENSCSAP00000016650	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.953
GNAO1	KCNJ6	ENSCSAP00000001466	ENSCSAP00000004726	G protein subunit alpha o1.	Potassium voltage-gated channel subfamily J member 6.	0.916

page 1 of 3

Server load: medium (52%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About