STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK1Hook microtubule tethering protein 1. (733 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
   
 0.856
HOOK3
Hook microtubule tethering protein 3.
  
 
0.699
FAM160A2
Family with sequence similarity 160 member A2.
    
 0.682
SNAPIN
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
      
 0.652
CCDC181
Coiled-coil domain containing 181.
     
 0.608
FAM160B1
Family with sequence similarity 160 member B1.
    
 0.588
TFEB
Transcription factor EB.
    
 0.560
CLN3
Battenin.
    
 
 0.543
SUN5
Sad1 and UNC84 domain containing 5.
    
 
 0.524
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 0.513
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (52%) [HD]