Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC20Cell division cycle 20. (499 aa)    
Predicted Functional Partners:
MAD2L1
HORMA domain-containing protein.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.999
BUB1B
BUB1 N-terminal domain-containing protein.
   
 0.999
FBXO5
F-box protein 5.
   
 0.999
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.998
ENSCSAP00000018428
Uncharacterized protein.
   
 0.998
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.997
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.997
BUB3
BUB3 mitotic checkpoint protein.
   
 0.996
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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