Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa)    
Predicted Functional Partners:
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
   
 
 0.853
CCDC102B
Coiled-coil domain containing 102B.
      
 0.785
PINK1
PTEN induced kinase 1.
      
 0.740
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
  
 0.718
PRKN
Parkin RBR E3 ubiquitin protein ligase.
      
 0.683
RIC3
RIC3 acetylcholine receptor chaperone.
    
 
 0.671
PARK7
Parkinsonism associated deglycase.
     
 0.666
GBA
Glucosylceramidase.
   
  
 0.640
PODXL
Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.
    
 0.626
TMEM175
Transmembrane protein 175.
      
 0.625
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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