Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPPANatriuretic peptide A. (153 aa)    
Predicted Functional Partners:
NPR1
Guanylate cyclase.
    
 0.998
NPR2
Guanylate cyclase.
    
 0.996
NPR3
Natriuretic peptide receptor 3.
    
 0.995
CORIN
Corin, serine peptidase.
     
 0.914
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.807
NPPB
Natriuretic peptide B.
   
  
 0.764
MYL7
Myosin light chain 7.
   
  
 0.755
GUCY2C
Guanylate cyclase.
    
 0.752
ADRB1
Adrenoceptor beta 1.
     
 0.748
TBX5
T-box transcription factor 5.
    
 0.725
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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