| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACOT13 | UBIAD1 | ENSCSAP00000004033 | ENSCSAP00000017214 | Acyl-CoA thioesterase 13. | UbiA prenyltransferase domain containing 1. | 0.930 |
| COQ2 | COQ5 | ENSCSAP00000000756 | ENSCSAP00000015783 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.695 |
| COQ2 | DHDDS | ENSCSAP00000000756 | ENSCSAP00000017033 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.888 |
| COQ2 | ENSCSAP00000010218 | ENSCSAP00000000756 | ENSCSAP00000010218 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.907 |
| COQ2 | HAO1 | ENSCSAP00000000756 | ENSCSAP00000009687 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Hydroxyacid oxidase 1. | 0.845 |
| COQ2 | HAO2 | ENSCSAP00000000756 | ENSCSAP00000016314 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Hydroxyacid oxidase 2. | 0.845 |
| COQ2 | HMGCR | ENSCSAP00000000756 | ENSCSAP00000011506 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.678 |
| COQ2 | IDI1 | ENSCSAP00000000756 | ENSCSAP00000010209 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 1. | 0.907 |
| COQ2 | NUS1 | ENSCSAP00000000756 | ENSCSAP00000012129 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.888 |
| COQ2 | UBIAD1 | ENSCSAP00000000756 | ENSCSAP00000017214 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | UbiA prenyltransferase domain containing 1. | 0.916 |
| COQ5 | COQ2 | ENSCSAP00000015783 | ENSCSAP00000000756 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.695 |
| COQ5 | UBIAD1 | ENSCSAP00000015783 | ENSCSAP00000017214 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | UbiA prenyltransferase domain containing 1. | 0.845 |
| DHDDS | COQ2 | ENSCSAP00000017033 | ENSCSAP00000000756 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.888 |
| DHDDS | ENSCSAP00000010218 | ENSCSAP00000017033 | ENSCSAP00000010218 | Alkyl transferase; Belongs to the UPP synthase family. | Nudix hydrolase domain-containing protein. | 0.739 |
| DHDDS | HAO1 | ENSCSAP00000017033 | ENSCSAP00000009687 | Alkyl transferase; Belongs to the UPP synthase family. | Hydroxyacid oxidase 1. | 0.664 |
| DHDDS | HAO2 | ENSCSAP00000017033 | ENSCSAP00000016314 | Alkyl transferase; Belongs to the UPP synthase family. | Hydroxyacid oxidase 2. | 0.664 |
| DHDDS | HMGCR | ENSCSAP00000017033 | ENSCSAP00000011506 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.522 |
| DHDDS | IDI1 | ENSCSAP00000017033 | ENSCSAP00000010209 | Alkyl transferase; Belongs to the UPP synthase family. | Isopentenyl-diphosphate delta isomerase 1. | 0.739 |
| DHDDS | NUS1 | ENSCSAP00000017033 | ENSCSAP00000012129 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.998 |
| DHDDS | UBIAD1 | ENSCSAP00000017033 | ENSCSAP00000017214 | Alkyl transferase; Belongs to the UPP synthase family. | UbiA prenyltransferase domain containing 1. | 0.852 |