| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACOT13 | UBIAD1 | ENSCSAP00000004033 | ENSCSAP00000017214 | Acyl-CoA thioesterase 13. | UbiA prenyltransferase domain containing 1. | 0.792 |
| COQ2 | COQ5 | ENSCSAP00000000756 | ENSCSAP00000015783 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.773 |
| COQ2 | DHDDS | ENSCSAP00000000756 | ENSCSAP00000017033 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.629 |
| COQ2 | GGCX | ENSCSAP00000000756 | ENSCSAP00000012253 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Gamma-glutamyl carboxylase. | 0.614 |
| COQ2 | HMGCR | ENSCSAP00000000756 | ENSCSAP00000011506 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.439 |
| COQ2 | NUS1 | ENSCSAP00000000756 | ENSCSAP00000012129 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.622 |
| COQ2 | UBIAD1 | ENSCSAP00000000756 | ENSCSAP00000017214 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | UbiA prenyltransferase domain containing 1. | 0.794 |
| COQ5 | COQ2 | ENSCSAP00000015783 | ENSCSAP00000000756 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.773 |
| COQ5 | HMGCR | ENSCSAP00000015783 | ENSCSAP00000011506 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.464 |
| COQ5 | UBIAD1 | ENSCSAP00000015783 | ENSCSAP00000017214 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | UbiA prenyltransferase domain containing 1. | 0.695 |
| DHDDS | COQ2 | ENSCSAP00000017033 | ENSCSAP00000000756 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.629 |
| DHDDS | HMGCR | ENSCSAP00000017033 | ENSCSAP00000011506 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.404 |
| DHDDS | NUS1 | ENSCSAP00000017033 | ENSCSAP00000012129 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.999 |
| DHDDS | UBIAD1 | ENSCSAP00000017033 | ENSCSAP00000017214 | Alkyl transferase; Belongs to the UPP synthase family. | UbiA prenyltransferase domain containing 1. | 0.602 |
| DISP3 | FBXO2 | ENSCSAP00000017213 | ENSCSAP00000017212 | Dispatched RND transporter family member 3. | F-box protein 2. | 0.607 |
| DISP3 | UBIAD1 | ENSCSAP00000017213 | ENSCSAP00000017214 | Dispatched RND transporter family member 3. | UbiA prenyltransferase domain containing 1. | 0.698 |
| FBXO2 | DISP3 | ENSCSAP00000017212 | ENSCSAP00000017213 | F-box protein 2. | Dispatched RND transporter family member 3. | 0.607 |
| FBXO2 | UBIAD1 | ENSCSAP00000017212 | ENSCSAP00000017214 | F-box protein 2. | UbiA prenyltransferase domain containing 1. | 0.567 |
| GGCX | COQ2 | ENSCSAP00000012253 | ENSCSAP00000000756 | Gamma-glutamyl carboxylase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.614 |
| GGCX | UBIAD1 | ENSCSAP00000012253 | ENSCSAP00000017214 | Gamma-glutamyl carboxylase. | UbiA prenyltransferase domain containing 1. | 0.553 |