| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENPP1 | ENPP3 | ENSCSAP00000012721 | ENSCSAP00000012716 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.918 |
| ENPP1 | NADK | ENSCSAP00000012721 | ENSCSAP00000017307 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | NAD kinase. | 0.935 |
| ENPP1 | NADK2 | ENSCSAP00000012721 | ENSCSAP00000013070 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | NAD kinase 2, mitochondrial. | 0.902 |
| ENPP1 | NADSYN1 | ENSCSAP00000012721 | ENSCSAP00000005682 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.909 |
| ENPP1 | NMNAT2 | ENSCSAP00000012721 | ENSCSAP00000008815 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Nicotinamide nucleotide adenylyltransferase 2. | 0.903 |
| ENPP1 | NMNAT3 | ENSCSAP00000012721 | ENSCSAP00000007379 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Nicotinamide-nucleotide adenylyltransferase. | 0.903 |
| ENPP1 | NNT | ENSCSAP00000012721 | ENSCSAP00000012804 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Nicotinamide nucleotide transhydrogenase. | 0.900 |
| ENPP1 | SARM1 | ENSCSAP00000012721 | ENSCSAP00000003569 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Sterile alpha and TIR motif containing 1. | 0.901 |
| ENPP1 | SIRT1 | ENSCSAP00000012721 | ENSCSAP00000003766 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Sirtuin 1. | 0.901 |
| ENPP1 | SIRT5 | ENSCSAP00000012721 | ENSCSAP00000003795 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.900 |
| ENPP3 | ENPP1 | ENSCSAP00000012716 | ENSCSAP00000012721 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.918 |
| ENPP3 | NADK | ENSCSAP00000012716 | ENSCSAP00000017307 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | NAD kinase. | 0.935 |
| ENPP3 | NADK2 | ENSCSAP00000012716 | ENSCSAP00000013070 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | NAD kinase 2, mitochondrial. | 0.902 |
| ENPP3 | NADSYN1 | ENSCSAP00000012716 | ENSCSAP00000005682 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.909 |
| ENPP3 | NMNAT2 | ENSCSAP00000012716 | ENSCSAP00000008815 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Nicotinamide nucleotide adenylyltransferase 2. | 0.901 |
| ENPP3 | NMNAT3 | ENSCSAP00000012716 | ENSCSAP00000007379 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Nicotinamide-nucleotide adenylyltransferase. | 0.903 |
| ENPP3 | NNT | ENSCSAP00000012716 | ENSCSAP00000012804 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Nicotinamide nucleotide transhydrogenase. | 0.900 |
| ENPP3 | SARM1 | ENSCSAP00000012716 | ENSCSAP00000003569 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Sterile alpha and TIR motif containing 1. | 0.901 |
| ENPP3 | SIRT1 | ENSCSAP00000012716 | ENSCSAP00000003766 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Sirtuin 1. | 0.901 |
| ENPP3 | SIRT5 | ENSCSAP00000012716 | ENSCSAP00000003795 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.900 |
