Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)    
Predicted Functional Partners:
BMP4
Bone morphogenetic protein 4.
    
 0.998
BMP2
Bone morphogenetic protein 2.
    
 0.996
BMP7
Bone morphogenetic protein 7.
    
 0.991
GDF5
Growth differentiation factor 5.
    
 0.985
BMP6
Bone morphogenetic protein 6.
    
 0.977
BMP5
Bone morphogenetic protein 5.
    
 0.977
GDF6
Growth differentiation factor 6.
    
 0.965
GDF7
Growth differentiation factor 7.
    
 0.964
ENSCSAP00000016878
TGF_BETA_2 domain-containing protein.
    
 0.924
AMH
Anti-Mullerian hormone.
    
 0.923
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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