Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
LOC103224743ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
LIMK1
LIM domain kinase 1.
   
 0.996
LOC103240948
Uncharacterized protein.
   
 0.994
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
  
 
0.992
LIMK2
LIM domain kinase 2.
   
 0.981
SSH3
Slingshot protein phosphatase 3.
    
 0.969
SSH2
Slingshot protein phosphatase 2.
    
 0.963
PFN1
Profilin; Belongs to the profilin family.
   
 0.961
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.865
WDR1
WD repeat domain 1.
   
 
 0.858
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.852
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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