STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APC2APC regulator of WNT signaling pathway 2. (1685 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.993
AXIN1
Axin 1.
   
 0.987
AXIN2
Axin 2.
   
 0.982
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.979
ARHGEF4
Rho guanine nucleotide exchange factor 4.
   
 0.964
CSNK1A1
Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.
    
 0.959
CSNK1A1L
Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily.
    
 0.959
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
     
 0.953
LEF1
Lymphoid enhancer binding factor 1.
    
 0.951
TCF7L1
Transcription factor 7 like 1.
    
 0.947
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.