STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (225 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.995
JAK1
Tyrosine-protein kinase.
   
 0.986
STAT1
Signal transducer and activator of transcription.
   
 0.976
STAT2
Signal transducer and activator of transcription.
   
 0.971
STAT3
Signal transducer and activator of transcription.
   
 0.969
LEPR
Leptin receptor.
    
 0.963
SOCS1
Suppressor of cytokine signaling 1.
   
 
0.956
SOCS2
Suppressor of cytokine signaling 2.
    
0.951
JAK3
Tyrosine-protein kinase.
   
 0.939
IRS2
Insulin receptor substrate 2.
    
 0.938
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.