node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADL41637.1 | ADL42699.1 | COB47_0290 | COB47_1409 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.957 |
ADL41637.1 | ADL43046.1 | COB47_0290 | COB47_1769 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.966 |
ADL41637.1 | ADL43048.1 | COB47_0290 | COB47_1771 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.693 |
ADL41637.1 | glyA | COB47_0290 | COB47_1465 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.960 |
ADL41637.1 | metX | COB47_0290 | COB47_1408 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.661 |
ADL42527.1 | glyA | COB47_1235 | COB47_1465 | PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
ADL42527.1 | metX | COB47_1235 | COB47_1408 | PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.800 |
ADL42527.1 | trpA | COB47_1235 | COB47_0895 | PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
ADL42527.1 | trpB | COB47_1235 | COB47_0894 | PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
ADL42696.1 | ADL42697.1 | COB47_1406 | COB47_1407 | KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase. | KEGG: ate:Athe_1126 beta-lactamase domain protein. | 0.695 |
ADL42696.1 | ADL42699.1 | COB47_1406 | COB47_1409 | KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.447 |
ADL42696.1 | metX | COB47_1406 | COB47_1408 | KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.686 |
ADL42697.1 | ADL42696.1 | COB47_1407 | COB47_1406 | KEGG: ate:Athe_1126 beta-lactamase domain protein. | KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase. | 0.695 |
ADL42697.1 | ADL42699.1 | COB47_1407 | COB47_1409 | KEGG: ate:Athe_1126 beta-lactamase domain protein. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.501 |
ADL42697.1 | metX | COB47_1407 | COB47_1408 | KEGG: ate:Athe_1126 beta-lactamase domain protein. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.782 |
ADL42699.1 | ADL41637.1 | COB47_1409 | COB47_0290 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.957 |
ADL42699.1 | ADL42696.1 | COB47_1409 | COB47_1406 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase. | 0.447 |
ADL42699.1 | ADL42697.1 | COB47_1409 | COB47_1407 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | KEGG: ate:Athe_1126 beta-lactamase domain protein. | 0.501 |
ADL42699.1 | ADL43046.1 | COB47_1409 | COB47_1769 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.888 |
ADL42699.1 | metX | COB47_1409 | COB47_1408 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.993 |