STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL43230.1KEGG: ate:Athe_2182 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein. (365 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.916
ADL42214.1
PFAM: phosphoribosyltransferase; KEGG: ate:Athe_1679 phosphoribosyltransferase.
 
 
 0.861
ADL43237.1
TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: ate:Athe_2193 Mg chelatase, subunit ChlI; SMART: AAA ATPase.
 
 0.859
ADL43008.1
KEGG: ate:Athe_1921 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
 
  
 0.854
trmFO
Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.782
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
   0.774
ADL43208.1
KEGG: ate:Athe_2160 CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein.
  
    0.746
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
       0.728
ADL42966.1
KEGG: ate:Athe_1879 peptidase A24A domain protein; PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV.
  
  
 0.722
ADL42824.1
PFAM: uncharacterized protein family UPF0102; KEGG: ate:Athe_0977 protein of unknown function UPF0102; Belongs to the UPF0102 family.
 
    0.683
Your Current Organism:
Caldicellulosiruptor obsidiansis
NCBI taxonomy Id: 608506
Other names: C. obsidiansis OB47, Caldicellulosiruptor obsidiansis OB47, Caldicellulosiruptor obsidiansis str. OB47, Caldicellulosiruptor obsidiansis strain OB47, Caldicellulosiruptor sp. OB47
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