Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFE92662.1Hypothetical protein. (74 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.773
recJ
KEGG: aoe:Clos_1716 4.9e-133 single-stranded-DNA-specific exonuclease RecJ; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87.
       0.773
EFE92661.1
Hypothetical protein.
       0.572
EFE92663.1
CAAX amino terminal protease family protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.572
Your Current Organism:
Oribacterium sp. F0262
NCBI taxonomy Id: 608534
Other names: O. sp. oral taxon 078 str. F0262, Oribacterium sp. oral taxon 078 str. F0262, Oribacterium sp. oral taxon 078 strain F0262
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