STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilC2Fimbrial assembly protein PilC. (394 aa)    
Predicted Functional Partners:
gspE
Type II secretion system protein E.
 
 0.931
pilB
Type IV pilus assembly protein.
 
 0.931
pulE
General secretion pathway protein E.
 
 0.931
pilD
Type 4 prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.822
pilT1
Twitching motility protein.
  
 0.794
pilT2
Twitching mobility protein.
  
 0.787
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.784
pilT3
Twitching mobility protein.
 
  
 0.734
HTH_0321
Hypothetical protein.
       0.714
pulK
General secretion pathway protein K.
  
  
 0.587
Your Current Organism:
Hydrogenobacter thermophilus
NCBI taxonomy Id: 608538
Other names: H. thermophilus TK-6, Hydrogenobacter thermophilus DSM 6534, Hydrogenobacter thermophilus TK-6, Hydrogenobacter thermophilus str. TK-6, Hydrogenobacter thermophilus strain TK-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.