node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HTH_1106 | frdA | HTH_1106 | HTH_1421 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate reductase subunit A. | 0.999 |
HTH_1106 | frdB | HTH_1106 | HTH_0983 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate reductase subunit B. | 0.914 |
HTH_1106 | frdD | HTH_1106 | HTH_1512 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate reductase subunit D. | 0.906 |
HTH_1106 | frdE | HTH_1106 | HTH_1863 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate reductase subunit E. | 0.906 |
HTH_1106 | fumA | HTH_1106 | HTH_0757 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate hydratase alpha subunit. | 0.936 |
HTH_1106 | fumB | HTH_1106 | HTH_0301 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | Fumarate hydratase beta subunit. | 0.936 |
HTH_1106 | nuoD1 | HTH_1106 | HTH_0414 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | NADH dehydrogenase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.980 |
HTH_1106 | nuoD2 | HTH_1106 | HTH_1413 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | NADH dehydrogenase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.978 |
HTH_1106 | sucC | HTH_1106 | HTH_1893 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.972 |
HTH_1106 | sucD | HTH_1106 | HTH_1892 | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.980 |
frdA | HTH_1106 | HTH_1421 | HTH_1106 | Fumarate reductase subunit A. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.999 |
frdA | frdB | HTH_1421 | HTH_0983 | Fumarate reductase subunit A. | Fumarate reductase subunit B. | 0.999 |
frdA | frdD | HTH_1421 | HTH_1512 | Fumarate reductase subunit A. | Fumarate reductase subunit D. | 0.908 |
frdA | frdE | HTH_1421 | HTH_1863 | Fumarate reductase subunit A. | Fumarate reductase subunit E. | 0.931 |
frdA | fumA | HTH_1421 | HTH_0757 | Fumarate reductase subunit A. | Fumarate hydratase alpha subunit. | 0.968 |
frdA | fumB | HTH_1421 | HTH_0301 | Fumarate reductase subunit A. | Fumarate hydratase beta subunit. | 0.968 |
frdA | nuoD1 | HTH_1421 | HTH_0414 | Fumarate reductase subunit A. | NADH dehydrogenase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.981 |
frdA | nuoD2 | HTH_1421 | HTH_1413 | Fumarate reductase subunit A. | NADH dehydrogenase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.981 |
frdA | sucC | HTH_1421 | HTH_1893 | Fumarate reductase subunit A. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.991 |
frdA | sucD | HTH_1421 | HTH_1892 | Fumarate reductase subunit A. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.992 |