STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htrAPeriplasmic serine protease. (474 aa)    
Predicted Functional Partners:
bioH
Putative biotin biosynthesis protein.
    
 0.897
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.828
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.808
bioC
Biotin biosynthesis protein.
       0.773
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.773
HTH_1587
Hypothetical protein.
    
 
 0.729
HTH_0588
Hypothetical protein.
   
 0.706
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.694
HTH_1862
Hypothetical protein.
       0.693
frdE
Fumarate reductase subunit E.
       0.693
Your Current Organism:
Hydrogenobacter thermophilus
NCBI taxonomy Id: 608538
Other names: H. thermophilus TK-6, Hydrogenobacter thermophilus DSM 6534, Hydrogenobacter thermophilus TK-6, Hydrogenobacter thermophilus str. TK-6, Hydrogenobacter thermophilus strain TK-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.