STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL03704.1KEGG: cpy:Cphy_0333 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr. (80 aa)    
Predicted Functional Partners:
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
 
 
 
 0.944
ADL03854.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.849
ADL06489.1
TIGRFAM: PTS system, mannitol-specific IIC subunit; KEGG: eca:ECA0087 PTS system, mannitol-specific IIABC component; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit.
 
 
 
 0.831
ADL06488.1
KEGG: cbe:Cbei_0242 PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit.
 
 
 
 0.830
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
  
 0.815
ADL03702.1
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.814
ADL06486.1
PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: amt:Amet_4269 PTS system, mannitol-specific IIC subunit.
   
 
 0.806
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
   
 0.797
ADL05008.1
KEGG: cbe:Cbei_1844 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC.
  
  
 0.725
ADL02842.1
KEGG: cbe:Cbei_4914 PTS system mannose/fructose/sorbose family IIA subunit; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component.
   
 
 0.674
Your Current Organism:
Clostridium saccharolyticum WM1
NCBI taxonomy Id: 610130
Other names: Clostridium saccharolyticum DSM 2544, [. saccharolyticum WM1, [Clostridium] saccharolyticum WM1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.