STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL04259.1KEGG: ere:EUBREC_1979 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein. (365 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.996
ADL03086.1
KEGG: ere:EUBREC_1954 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II.
 
 0.978
hisC
PFAM: aminotransferase class I and II; KEGG: eel:EUBELI_00629 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.970
ADL04260.1
KEGG: cpy:Cphy_2538 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA.
 
 0.961
ADL03864.1
PFAM: aminotransferase class I and II; KEGG: eel:EUBELI_00628 aspartate aminotransferase.
  
 
 0.918
ADL03244.1
PFAM: amino acid-binding ACT domain protein; KEGG: ere:EUBREC_0723 hypothetical protein; Belongs to the UPF0735 family.
     
 0.910
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.828
aroK-2
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.822
ADL03033.1
PFAM: phosphoribosyltransferase; KEGG: cpy:Cphy_0248 amidophosphoribosyltransferase.
  
  
 0.761
cmk
KEGG: ere:EUBREC_1636 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
 
  
 0.757
Your Current Organism:
Clostridium saccharolyticum WM1
NCBI taxonomy Id: 610130
Other names: Clostridium saccharolyticum DSM 2544, [. saccharolyticum WM1, [Clostridium] saccharolyticum WM1
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