STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL06475.1PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cpf:CPF_0084 myo-inositol catabolism protein IolD; Belongs to the TPP enzyme family. (643 aa)    
Predicted Functional Partners:
iolE
Myo-inosose-2 dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
 
 
 0.999
ADL06472.1
KEGG: str:Sterm_4017 myo-inositol catabolism IolB domain protein.
 
 
 0.998
iolC
PfkB domain protein; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
 
  
 0.970
ADL06473.1
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: str:Sterm_4014 oxidoreductase domain protein.
 
  
 0.958
ADL06477.1
KEGG: str:Sterm_4016 methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
 
  
 0.935
ADL04318.1
PFAM: Aldehyde Dehydrogenase; KEGG: dds:Ddes_1981 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.782
ADL02977.1
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: gym:GYMC10_4658 oxidoreductase domain protein.
 
  
 0.708
ADL02979.1
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: str:Sterm_4053 oxidoreductase domain protein.
 
  
 0.691
ADL06356.1
PFAM: oxidoreductase domain protein; KEGG: amt:Amet_0460 oxidoreductase domain-containing protein.
 
  
 0.663
ADL06710.1
PFAM: PfkB domain protein; KEGG: sus:Acid_1926 ribokinase-like domain-containing protein.
 
  
 0.636
Your Current Organism:
Clostridium saccharolyticum WM1
NCBI taxonomy Id: 610130
Other names: Clostridium saccharolyticum DSM 2544, [. saccharolyticum WM1, [Clostridium] saccharolyticum WM1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.