STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAI_04367Voltage-dependent calcium channel subunit alpha-2/delta-3. (1200 aa)    
Predicted Functional Partners:
EAI_03516
Voltage-dependent L-type calcium channel subunit beta-2.
   
 0.827
EAI_08460
Sodium channel protein 60E.
   
 0.545
EAI_08461
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.545
EAI_01156
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.545
EAI_13848
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 0.545
EAI_13849
Voltage-dependent calcium channel type D subunit alpha-1.
   
 0.545
EAI_02242
Two pore calcium channel protein 1.
   
 0.545
EAI_07572
Voltage-dependent calcium channel type A subunit alpha-1.
   
 0.545
EAI_07266
Sodium leak channel non-selective protein.
   
 0.539
EAI_01728
Tetratricopeptide repeat protein 21B.
    
 0.416
Your Current Organism:
Harpegnathos saltator
NCBI taxonomy Id: 610380
Other names: H. saltator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.