STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAI_14524Forkhead transcription factor HCM1. (578 aa)    
Predicted Functional Partners:
EAI_04303
GATA-binding factor A.
  
 
 0.553
EAI_11725
GATA-binding factor A.
  
 
 0.479
EAI_04796
Non-specific serine/threonine protein kinase.
    
 0.475
EAI_16218
CREB-binding protein.
    
 0.470
EAI_16219
Histone acetyltransferase p300.
    
 0.470
EAI_01666
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.443
EAI_11724
Transcription factor GATA-4.
  
 
 0.422
EAI_07262
Leucine-rich repeat serine/threonine-protein kinase 2.
    
 0.419
EAI_03751
NAD-dependent deacetylase sirtuin-1.
    
 0.417
EAI_11517
NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
    
 0.417
Your Current Organism:
Harpegnathos saltator
NCBI taxonomy Id: 610380
Other names: H. saltator
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.