HMGCR protein (Varanus komodoensis) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase. (882 aa)

Predicted Functional Partners:

HMGCS1

0.995

HMGCS2

0.994

UBIAD1

0.953

MVD

0.938

SQLE

0.929

ENSVKKP00000027455

0.922

ENSVKKP00000027457

0.922

CYP51A1

0.919

INSIG1

0.882

INSIG2

0.882

Your Current Organism:

Varanus komodoensis

NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP51A1	HMGCR	ENSVKKP00000024849	ENSVKKP00000001948	Cytochrome P450 family 51 subfamily A member 1.	3-hydroxy-3-methylglutaryl-CoA reductase.	0.919
CYP51A1	HMGCS1	ENSVKKP00000024849	ENSVKKP00000001603	Cytochrome P450 family 51 subfamily A member 1.	3-hydroxy-3-methylglutaryl-CoA synthase 1.	0.946
CYP51A1	HMGCS2	ENSVKKP00000024849	ENSVKKP00000020443	Cytochrome P450 family 51 subfamily A member 1.	3-hydroxy-3-methylglutaryl-CoA synthase 2.	0.897
CYP51A1	INSIG1	ENSVKKP00000024849	ENSVKKP00000000912	Cytochrome P450 family 51 subfamily A member 1.	Insulin induced gene 1.	0.505
CYP51A1	INSIG2	ENSVKKP00000024849	ENSVKKP00000004269	Cytochrome P450 family 51 subfamily A member 1.	Insulin induced gene 2.	0.505
CYP51A1	MVD	ENSVKKP00000024849	ENSVKKP00000021085	Cytochrome P450 family 51 subfamily A member 1.	Mevalonate diphosphate decarboxylase.	0.857
CYP51A1	SQLE	ENSVKKP00000024849	ENSVKKP00000005573	Cytochrome P450 family 51 subfamily A member 1.	Squalene epoxidase.	0.998
ENSVKKP00000027455	HMGCR	ENSVKKP00000027455	ENSVKKP00000001948	annotation not available	3-hydroxy-3-methylglutaryl-CoA reductase.	0.922
ENSVKKP00000027455	HMGCS1	ENSVKKP00000027455	ENSVKKP00000001603	annotation not available	3-hydroxy-3-methylglutaryl-CoA synthase 1.	0.834
ENSVKKP00000027455	HMGCS2	ENSVKKP00000027455	ENSVKKP00000020443	annotation not available	3-hydroxy-3-methylglutaryl-CoA synthase 2.	0.834
ENSVKKP00000027455	MVD	ENSVKKP00000027455	ENSVKKP00000021085	annotation not available	Mevalonate diphosphate decarboxylase.	0.982
ENSVKKP00000027455	SQLE	ENSVKKP00000027455	ENSVKKP00000005573	annotation not available	Squalene epoxidase.	0.545
ENSVKKP00000027457	HMGCR	ENSVKKP00000027457	ENSVKKP00000001948	annotation not available	3-hydroxy-3-methylglutaryl-CoA reductase.	0.922
ENSVKKP00000027457	HMGCS1	ENSVKKP00000027457	ENSVKKP00000001603	annotation not available	3-hydroxy-3-methylglutaryl-CoA synthase 1.	0.834
ENSVKKP00000027457	HMGCS2	ENSVKKP00000027457	ENSVKKP00000020443	annotation not available	3-hydroxy-3-methylglutaryl-CoA synthase 2.	0.834
ENSVKKP00000027457	MVD	ENSVKKP00000027457	ENSVKKP00000021085	annotation not available	Mevalonate diphosphate decarboxylase.	0.982
ENSVKKP00000027457	SQLE	ENSVKKP00000027457	ENSVKKP00000005573	annotation not available	Squalene epoxidase.	0.545
HMGCR	CYP51A1	ENSVKKP00000001948	ENSVKKP00000024849	3-hydroxy-3-methylglutaryl-CoA reductase.	Cytochrome P450 family 51 subfamily A member 1.	0.919
HMGCR	ENSVKKP00000027455	ENSVKKP00000001948	ENSVKKP00000027455	3-hydroxy-3-methylglutaryl-CoA reductase.	annotation not available	0.922
HMGCR	ENSVKKP00000027457	ENSVKKP00000001948	ENSVKKP00000027457	3-hydroxy-3-methylglutaryl-CoA reductase.	annotation not available	0.922