STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)    
Predicted Functional Partners:
MRAS
Muscle RAS oncogene homolog.
    
 0.993
PPP1CC
Protein phosphatase 1 catalytic subunit gamma.
    
 0.929
ENSVKKP00000014246
annotation not available
    
 0.929
ENSVKKP00000026261
annotation not available
    
 0.929
PPP1CB
Protein phosphatase 1 catalytic subunit beta.
   
 0.888
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
   
  0.865
RRAS
RAS related.
    
 0.852
RRAS2
RAS related 2.
    
 0.852
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
 
  
 0.848
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
 
  
 0.848
Your Current Organism:
Varanus komodoensis
NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.