STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHLD2Shieldin complex subunit 2. (890 aa)    
Predicted Functional Partners:
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 
 0.973
SHLD1
Shieldin complex subunit 1.
    
 
 0.677
RIF1
Replication timing regulatory factor 1.
    
 
 0.506
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
      
 0.429
ENSVKKP00000006055
annotation not available
      
 0.416
COPS6
COP9 signalosome subunit 6.
      
 0.410
Your Current Organism:
Varanus komodoensis
NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.