STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELQHelicase, POLQ like. (1043 aa)    
Predicted Functional Partners:
POLA1
DNA polymerase alpha 1, catalytic subunit.
   
 0.913
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.896
POLD1
DNA polymerase delta 1, catalytic subunit.
   
 0.871
POLE2
DNA polymerase epsilon 2, accessory subunit.
   
 
 0.867
ENSVKKP00000009391
annotation not available
   
 
 0.845
ENSVKKP00000009393
annotation not available
   
 
 0.845
POLG
DNA polymerase gamma, catalytic subunit.
   
 
 0.836
FANCD2
FA complementation group D2.
   
 0.835
ENSVKKP00000024533
annotation not available
   
 0.834
DNA2
DNA replication helicase/nuclease 2.
   
 
 0.824
Your Current Organism:
Varanus komodoensis
NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.