FGD4 protein (Varanus komodoensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

Experiments

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[Homology]

Score

FGD4

FYVE, RhoGEF and PH domain containing 4. (901 aa)

Predicted Functional Partners:

CDC42

0.819

PIGN

0.720

SH3TC2

0.589

RAC3

0.521

RAC2

0.521

RAC1

0.521

FAM234A

0.519

ENSVKKP00000001482

0.519

RHOV

0.519

UTP11

0.519

Your Current Organism:

Varanus komodoensis

NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSVKKP00000001482	ENSVKKP00000010863	ENSVKKP00000001482	Cell division cycle 42.	annotation not available	0.652
CDC42	FGD4	ENSVKKP00000010863	ENSVKKP00000020528	Cell division cycle 42.	FYVE, RhoGEF and PH domain containing 4.	0.819
CDC42	RAC1	ENSVKKP00000010863	ENSVKKP00000011405	Cell division cycle 42.	Rac family small GTPase 1.	0.803
CDC42	RAC2	ENSVKKP00000010863	ENSVKKP00000009166	Cell division cycle 42.	Rac family small GTPase 2.	0.802
CDC42	RAC3	ENSVKKP00000010863	ENSVKKP00000006557	Cell division cycle 42.	Rac family small GTPase 3.	0.803
CDC42	RHOV	ENSVKKP00000010863	ENSVKKP00000013767	Cell division cycle 42.	Ras homolog family member V.	0.655
ENSVKKP00000001482	CDC42	ENSVKKP00000001482	ENSVKKP00000010863	annotation not available	Cell division cycle 42.	0.652
ENSVKKP00000001482	FGD4	ENSVKKP00000001482	ENSVKKP00000020528	annotation not available	FYVE, RhoGEF and PH domain containing 4.	0.519
ENSVKKP00000001482	RAC1	ENSVKKP00000001482	ENSVKKP00000011405	annotation not available	Rac family small GTPase 1.	0.623
ENSVKKP00000001482	RAC2	ENSVKKP00000001482	ENSVKKP00000009166	annotation not available	Rac family small GTPase 2.	0.623
ENSVKKP00000001482	RAC3	ENSVKKP00000001482	ENSVKKP00000006557	annotation not available	Rac family small GTPase 3.	0.623
FAM234A	FGD4	ENSVKKP00000000043	ENSVKKP00000020528	Family with sequence similarity 234 member A.	FYVE, RhoGEF and PH domain containing 4.	0.519
FGD4	CDC42	ENSVKKP00000020528	ENSVKKP00000010863	FYVE, RhoGEF and PH domain containing 4.	Cell division cycle 42.	0.819
FGD4	ENSVKKP00000001482	ENSVKKP00000020528	ENSVKKP00000001482	FYVE, RhoGEF and PH domain containing 4.	annotation not available	0.519
FGD4	FAM234A	ENSVKKP00000020528	ENSVKKP00000000043	FYVE, RhoGEF and PH domain containing 4.	Family with sequence similarity 234 member A.	0.519
FGD4	PIGN	ENSVKKP00000020528	ENSVKKP00000014984	FYVE, RhoGEF and PH domain containing 4.	Phosphatidylinositol glycan anchor biosynthesis class N.	0.720
FGD4	RAC1	ENSVKKP00000020528	ENSVKKP00000011405	FYVE, RhoGEF and PH domain containing 4.	Rac family small GTPase 1.	0.521
FGD4	RAC2	ENSVKKP00000020528	ENSVKKP00000009166	FYVE, RhoGEF and PH domain containing 4.	Rac family small GTPase 2.	0.521
FGD4	RAC3	ENSVKKP00000020528	ENSVKKP00000006557	FYVE, RhoGEF and PH domain containing 4.	Rac family small GTPase 3.	0.521
FGD4	RHOV	ENSVKKP00000020528	ENSVKKP00000013767	FYVE, RhoGEF and PH domain containing 4.	Ras homolog family member V.	0.519