RPS6KA6 protein (Varanus komodoensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RPS6KA6

Ribosomal protein S6 kinase A6. (734 aa)

Predicted Functional Partners:

MAPK3

0.957

TSC1

0.920

TBC1D7

0.909

ATF4

0.905

ENSVKKP00000024700

0.902

ENSVKKP00000024701

0.902

RPS6KA2

0.874

STX18

0.871

RINT1

0.869

ZW10

0.846

Your Current Organism:

Varanus komodoensis

NCBI taxonomy Id: 61221
Other names: Komodo dragon, Komodowaran, V. komodoensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	MAPK3	ENSVKKP00000024991	ENSVKKP00000008028	Activating transcription factor 4.	Mitogen-activated protein kinase 3.	0.690
ATF4	RPS6KA2	ENSVKKP00000024991	ENSVKKP00000025473	Activating transcription factor 4.	Ribosomal protein S6 kinase A2.	0.904
ATF4	RPS6KA6	ENSVKKP00000024991	ENSVKKP00000021916	Activating transcription factor 4.	Ribosomal protein S6 kinase A6.	0.905
ENSVKKP00000024700	ENSVKKP00000024701	ENSVKKP00000024700	ENSVKKP00000024701	annotation not available	annotation not available	0.923
ENSVKKP00000024700	MAPK3	ENSVKKP00000024700	ENSVKKP00000008028	annotation not available	Mitogen-activated protein kinase 3.	0.875
ENSVKKP00000024700	RPS6KA2	ENSVKKP00000024700	ENSVKKP00000025473	annotation not available	Ribosomal protein S6 kinase A2.	0.902
ENSVKKP00000024700	RPS6KA6	ENSVKKP00000024700	ENSVKKP00000021916	annotation not available	Ribosomal protein S6 kinase A6.	0.902
ENSVKKP00000024700	TBC1D7	ENSVKKP00000024700	ENSVKKP00000007551	annotation not available	TBC1 domain family member 7.	0.992
ENSVKKP00000024700	TSC1	ENSVKKP00000024700	ENSVKKP00000003206	annotation not available	TSC complex subunit 1.	0.991
ENSVKKP00000024701	ENSVKKP00000024700	ENSVKKP00000024701	ENSVKKP00000024700	annotation not available	annotation not available	0.923
ENSVKKP00000024701	MAPK3	ENSVKKP00000024701	ENSVKKP00000008028	annotation not available	Mitogen-activated protein kinase 3.	0.875
ENSVKKP00000024701	RPS6KA2	ENSVKKP00000024701	ENSVKKP00000025473	annotation not available	Ribosomal protein S6 kinase A2.	0.902
ENSVKKP00000024701	RPS6KA6	ENSVKKP00000024701	ENSVKKP00000021916	annotation not available	Ribosomal protein S6 kinase A6.	0.902
ENSVKKP00000024701	TBC1D7	ENSVKKP00000024701	ENSVKKP00000007551	annotation not available	TBC1 domain family member 7.	0.992
ENSVKKP00000024701	TSC1	ENSVKKP00000024701	ENSVKKP00000003206	annotation not available	TSC complex subunit 1.	0.991
MAPK3	ATF4	ENSVKKP00000008028	ENSVKKP00000024991	Mitogen-activated protein kinase 3.	Activating transcription factor 4.	0.690
MAPK3	ENSVKKP00000024700	ENSVKKP00000008028	ENSVKKP00000024700	Mitogen-activated protein kinase 3.	annotation not available	0.875
MAPK3	ENSVKKP00000024701	ENSVKKP00000008028	ENSVKKP00000024701	Mitogen-activated protein kinase 3.	annotation not available	0.875
MAPK3	RPS6KA2	ENSVKKP00000008028	ENSVKKP00000025473	Mitogen-activated protein kinase 3.	Ribosomal protein S6 kinase A2.	0.959
MAPK3	RPS6KA6	ENSVKKP00000008028	ENSVKKP00000021916	Mitogen-activated protein kinase 3.	Ribosomal protein S6 kinase A6.	0.957