STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP6Group XIIA secretory phospholipase A2. (431 aa)    
Predicted Functional Partners:
CASP9
Caspase 9.
    
0.952
CASP8
Caspase 8.
   
0.935
LMNA
Lamin A/C.
   
 0.934
APAF1
Apoptotic peptidase activating factor 1.
    
 0.927
LMNB1
Lamin B1.
   
 0.925
SATB1
SATB homeobox 1.
    
 0.909
LMNB2
Lamin B2.
   
 0.879
CASP10
Caspase 10.
   
0.748
CASP3
Caspase 3.
    
0.741
CENPN
Centromere protein N.
   
 0.726
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.