STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE2TLE family member 2, transcriptional corepressor. (744 aa)    
Predicted Functional Partners:
NRIP1
Nuclear receptor interacting protein 1.
     
 0.888
FOXA1
Forkhead box A1.
    
 0.851
GATA3
GATA binding protein 3.
     
 0.837
TCF7L2
Transcription factor 7 like 2.
    
 0.802
LEF1
Lymphoid enhancer binding factor 1.
    
 0.794
TLE1
Transducin-like enhancer protein 1.
  
 
 
0.733
CTNNB1
Catenin beta 1.
    
 0.731
LDB1
LIM domain binding 1.
    
 0.656
TCF4
Transcription factor 4.
   
 0.645
TLE4
TLE family member 4, transcriptional corepressor.
  
  
 
0.636
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.