STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTK2BProtein tyrosine kinase 2 beta. (1007 aa)    
Predicted Functional Partners:
PXN
Paxillin.
    
 0.981
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.973
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
   
0.970
LYN
LYN proto-oncogene, Src family tyrosine kinase.
   
0.959
CRK
CRK proto-oncogene, adaptor protein.
    
 0.950
JAK3
Janus kinase 3.
   
0.943
PTK2
Protein tyrosine kinase 2.
  
 
0.943
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.940
FGR
FGR proto-oncogene, Src family tyrosine kinase.
   
0.937
ITGB1
Integrin subunit beta 1.
   
 0.933
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.