STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR1Early growth response 1. (542 aa)    
Predicted Functional Partners:
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.948
EGR2
Early growth response 2.
   
 
0.929
MAPK1
Mitogen-activated protein kinase 1.
   
 0.927
MAPK3
Mitogen-activated protein kinase 3.
   
 0.925
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
   
 0.905
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
   
 0.905
IER2
Immediate early response 2.
   
  
 0.844
NAB2
NGFI-A binding protein 2.
   
 0.821
ENSLCNP00005019233
annotation not available
   
  
 0.784
TP53
Tumor protein p53.
   
 0.782
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.