STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAB1DAB adaptor protein 1. (588 aa)    
Predicted Functional Partners:
VLDLR
Very low density lipoprotein receptor.
    
 0.969
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.948
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.932
LRP8
LDL receptor related protein 8.
    
 0.925
LOC115519995
Phosphatidylinositol 3-kinase regulatory subunit gamma.
    
 0.919
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 
  0.910
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
   
 
  0.910
ITSN2
Intersectin 2.
   
 0.903
PIK3R2
Phosphoinositide-3-kinase regulatory subunit 2.
    
 0.879
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
   
 
  0.866
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.