STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF25Rho guanine nucleotide exchange factor 25. (619 aa)    
Predicted Functional Partners:
GNA14
G protein subunit alpha 14.
    
 0.767
GNA11
G protein subunit alpha 11.
    
 0.719
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha.
    
 0.719
RHOB
Ras homolog family member B.
    
 0.709
RHOA
Ras homolog family member A.
    
 0.709
GNA15
G protein subunit alpha 15.
    
 0.652
RHOBTB3
Rho related BTB domain containing 3.
    
 0.597
RND3
Rho family GTPase 3.
   
 0.588
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.586
BRS3
Bombesin receptor subtype 3.
   
 
  0.563
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.