STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNAR1Interferon alpha and beta receptor subunit 1. (560 aa)    
Predicted Functional Partners:
TYK2
Tyrosine kinase 2.
   
 0.999
IFNAR2
Interferon alpha and beta receptor subunit 2.
   
 0.999
JAK1
Janus kinase 1.
   
 0.995
STAT2
Signal transducer and activator of transcription 2.
   
 0.988
STAT1
Signal transducer and activator of transcription 1.
   
 0.984
IFNE
Interferon epsilon.
   
 0.979
IFNG
Interferon gamma.
     
 0.977
IFNGR1
Interferon gamma receptor 1.
   
 0.975
IL10
Interleukin 10.
    
 0.969
JAK2
Janus kinase 2.
   
 0.960
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.