STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE2Prickle planar cell polarity protein 2. (901 aa)    
Predicted Functional Partners:
VANGL1
VANGL planar cell polarity protein 1.
    
 0.982
DVL2
Dishevelled segment polarity protein 2.
    
 0.961
DVL1
Dishevelled segment polarity protein 1.
    
 0.961
VANGL2
VANGL planar cell polarity protein 2.
    
 0.958
DVL3
Dishevelled segment polarity protein 3.
    
 0.912
PRICKLE3
Prickle planar cell polarity protein 3.
  
  
 
0.911
PRICKLE1
Prickle planar cell polarity protein 1.
    
 
0.876
PRICKLE4
Prickle planar cell polarity protein 4.
    
 
0.820
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1.
   
 0.748
INVS
Inversin.
    
 0.663
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.