STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1445 aa)    
Predicted Functional Partners:
PTEN
Phosphatase and tensin homolog.
    
 0.924
IGSF5
Immunoglobulin superfamily member 5.
    
 0.919
SYNPO
Synaptopodin.
    
 0.917
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.910
CTNNB1
Catenin beta 1.
    
 0.906
RAPGEF6
Rap guanine nucleotide exchange factor 6.
    
 0.897
ACTN4
Actinin alpha 4.
    
 0.896
ACTN1
Actinin alpha 1.
    
 0.893
PARD3
Par-3 family cell polarity regulator.
    
 
0.881
PRKCI
Protein kinase C iota.
    
 0.878
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.