STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (855 aa)    
Predicted Functional Partners:
CDH1
Cadherin 1.
   
 0.991
CTNNB1
Catenin beta 1.
  
 
0.990
APC
APC regulator of WNT signaling pathway.
   
 0.981
LEF1
Lymphoid enhancer binding factor 1.
    
 0.971
TCF7L1
Transcription factor 7 like 1.
    
 0.971
ENSLCNP00005001400
annotation not available
   
 0.968
TCF7L2
Transcription factor 7 like 2.
    
 0.955
TCF7
Transcription factor 7.
    
 0.954
CCDC130
Coiled-coil domain containing 130.
   
   0.946
CDH3
Cadherin 3.
   
 0.942
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.