STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCF7L2Transcription factor 7 like 2. (673 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.999
JUP
Junction plakoglobin.
    
 0.955
NLK
Nemo like kinase.
    
 0.950
AXIN2
Axin 2.
   
 0.936
CREBBP
CREB binding protein.
   
 0.902
SMAD4
SMAD family member 4.
    
 0.899
ENSLCNP00005022639
annotation not available
   
 0.898
LEF1
Lymphoid enhancer binding factor 1.
    
0.895
CTBP2
C-terminal binding protein 2.
    
 0.889
CTBP1
C-terminal binding protein 1.
    
 0.886
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.