STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF8Interferon regulatory factor 8. (434 aa)    
Predicted Functional Partners:
IRF1
Interferon regulatory factor 1.
   
0.786
BATF3
Basic leucine zipper ATF-like transcription factor 3.
   
 
 0.762
SPI1
Spi-1 proto-oncogene.
   
 
 0.720
SPIB
Spi-B transcription factor.
   
 
 0.712
TRAF6
TNF receptor associated factor 6.
   
 0.685
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.652
CD4
CD4 molecule.
   
 
 0.642
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.633
STAT1
Signal transducer and activator of transcription 1.
   
 0.629
CEBPE
CCAAT enhancer binding protein epsilon.
    
 
 0.628
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.