STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT3Sirtuin 3. (372 aa)    
Predicted Functional Partners:
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.959
FOXO3
Forkhead box O3.
    
 0.954
NADSYN1
NAD synthetase 1.
    
 0.932
NMNAT2
Nicotinamide nucleotide adenylyltransferase 2.
    
 0.932
ACSS1
acyl-CoA synthetase short chain family member 1.
    
 0.930
CD38
CD38 molecule.
     
 0.924
NUDT12
Nudix hydrolase 12.
    
 0.919
PNP
Purine nucleoside phosphorylase.
    
 0.918
NADK
NAD kinase.
  
 
 0.918
NNT
Nicotinamide nucleotide transhydrogenase.
   
 
 0.917
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.