STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC1Arrestin domain containing 1. (431 aa)    
Predicted Functional Partners:
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 0.906
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 0.725
RAB22A
RAB22A, member RAS oncogene family.
    
 
 0.719
CEP55
Centrosomal protein 55.
      
 0.676
WWP1
WW domain containing E3 ubiquitin protein ligase 1.
    
 0.672
ITCH
Itchy E3 ubiquitin protein ligase.
    
 0.625
TSG101
Tumor susceptibility 101.
    
 
 0.624
PLEKHA5
Pleckstrin homology domain containing A5.
    
 0.542
TOM1L1
Target of myb1 like 1 membrane trafficking protein.
      
 0.524
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.518
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.