STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MADDMAP kinase activating death domain. (1647 aa)    
Predicted Functional Partners:
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.786
TNF
Tumor necrosis factor.
     
 0.781
FNBP4
Formin binding protein 4.
      
 0.765
PIBF1
Progesterone immunomodulatory binding factor 1.
      
 0.763
CKAP5
Cytoskeleton associated protein 5.
      
 0.754
ENSLCNP00005003430
annotation not available
      
 0.690
RAB27A
RAB27A, member RAS oncogene family.
     
 0.658
RAB27B
RAB27B, member RAS oncogene family.
     
 0.658
GDI2
GDP dissociation inhibitor 2.
     
 0.590
DDB2
Damage specific DNA binding protein 2.
      
 0.569
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.