STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV2Vav guanine nucleotide exchange factor 2. (756 aa)    
Predicted Functional Partners:
SYK
Spleen associated tyrosine kinase.
   
 0.922
LCP2
Lymphocyte cytosolic protein 2.
   
 0.905
RAC2
Rac family small GTPase 2.
   
 0.888
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.875
TIAM1
TIAM Rac1 associated GEF 1.
     
0.874
ENSLCNP00005018662
annotation not available
 
      0.874
CD19
CD19 molecule.
   
 0.853
PLCG1
Phospholipase C gamma 1.
   
0.850
CDC42
Cell division cycle 42.
   
 0.845
ENSLCNP00005027979
annotation not available
   
 0.845
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.