A0A1Y1WDF9 protein (Linderina pennispora) - STRING interaction network

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Predicted Interactions

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Score

A0A1Y1WDF9

Indoleamine 2,3-dioxygenase. (399 aa)

Predicted Functional Partners:

BNA5

0.812

A0A1Y1WKE2

0.785

A0A1Y1W9G6

0.751

A0A1Y1W4Q5

0.709

A0A1Y1W897

0.697

A0A1Y1WK25

0.674

A0A1Y1W7H0

0.653

A0A1Y1W7P9

0.653

A0A1Y1VZ75

0.603

A0A1Y1WM34

0.603

Your Current Organism:

Linderina pennispora

NCBI taxonomy Id: 61395
Other names: ATCC 12442, CBS 312.51, L. pennispora, NRRL 2237

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1Y1VZ75	A0A1Y1W4Q5	A0A1Y1VZ75	A0A1Y1W4Q5	PLP-dependent transferase.	Amino_oxidase domain-containing protein.	0.675
A0A1Y1VZ75	A0A1Y1W9G6	A0A1Y1VZ75	A0A1Y1W9G6	PLP-dependent transferase.	PLP-dependent transferase.	0.793
A0A1Y1VZ75	A0A1Y1WDF9	A0A1Y1VZ75	A0A1Y1WDF9	PLP-dependent transferase.	Indoleamine 2,3-dioxygenase.	0.603
A0A1Y1VZ75	BNA5	A0A1Y1VZ75	A0A1Y1WI88	PLP-dependent transferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.768
A0A1Y1W4Q5	A0A1Y1VZ75	A0A1Y1W4Q5	A0A1Y1VZ75	Amino_oxidase domain-containing protein.	PLP-dependent transferase.	0.675
A0A1Y1W4Q5	A0A1Y1W7H0	A0A1Y1W4Q5	A0A1Y1W7H0	Amino_oxidase domain-containing protein.	Tetrameric phenylalanine hydroxylase.	0.701
A0A1Y1W4Q5	A0A1Y1W7P9	A0A1Y1W4Q5	A0A1Y1W7P9	Amino_oxidase domain-containing protein.	Tyrosine 3-monooxygenase.	0.701
A0A1Y1W4Q5	A0A1Y1W897	A0A1Y1W4Q5	A0A1Y1W897	Amino_oxidase domain-containing protein.	Acyl-CoA N-acyltransferase.	0.748
A0A1Y1W4Q5	A0A1Y1W9G6	A0A1Y1W4Q5	A0A1Y1W9G6	Amino_oxidase domain-containing protein.	PLP-dependent transferase.	0.481
A0A1Y1W4Q5	A0A1Y1WDF9	A0A1Y1W4Q5	A0A1Y1WDF9	Amino_oxidase domain-containing protein.	Indoleamine 2,3-dioxygenase.	0.709
A0A1Y1W4Q5	A0A1Y1WM34	A0A1Y1W4Q5	A0A1Y1WM34	Amino_oxidase domain-containing protein.	PLP-dependent transferase.	0.675
A0A1Y1W7H0	A0A1Y1W4Q5	A0A1Y1W7H0	A0A1Y1W4Q5	Tetrameric phenylalanine hydroxylase.	Amino_oxidase domain-containing protein.	0.701
A0A1Y1W7H0	A0A1Y1W9G6	A0A1Y1W7H0	A0A1Y1W9G6	Tetrameric phenylalanine hydroxylase.	PLP-dependent transferase.	0.703
A0A1Y1W7H0	A0A1Y1WDF9	A0A1Y1W7H0	A0A1Y1WDF9	Tetrameric phenylalanine hydroxylase.	Indoleamine 2,3-dioxygenase.	0.653
A0A1Y1W7P9	A0A1Y1W4Q5	A0A1Y1W7P9	A0A1Y1W4Q5	Tyrosine 3-monooxygenase.	Amino_oxidase domain-containing protein.	0.701
A0A1Y1W7P9	A0A1Y1W9G6	A0A1Y1W7P9	A0A1Y1W9G6	Tyrosine 3-monooxygenase.	PLP-dependent transferase.	0.703
A0A1Y1W7P9	A0A1Y1WDF9	A0A1Y1W7P9	A0A1Y1WDF9	Tyrosine 3-monooxygenase.	Indoleamine 2,3-dioxygenase.	0.653
A0A1Y1W897	A0A1Y1W4Q5	A0A1Y1W897	A0A1Y1W4Q5	Acyl-CoA N-acyltransferase.	Amino_oxidase domain-containing protein.	0.748
A0A1Y1W897	A0A1Y1WDF9	A0A1Y1W897	A0A1Y1WDF9	Acyl-CoA N-acyltransferase.	Indoleamine 2,3-dioxygenase.	0.697
A0A1Y1W9G6	A0A1Y1VZ75	A0A1Y1W9G6	A0A1Y1VZ75	PLP-dependent transferase.	PLP-dependent transferase.	0.793

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Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.824

expected number of edges:

25

PPI enrichment p-value:

0.0784

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

3 of 3

2.4

1.73

0.00059

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

3 of 6

2.1

1.59

0.00082

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1750

Polyketide synthase, phosphopantetheine-binding domain, and Thioesterase

4 of 6

2.22

2.57

8.71e-06

CL:1702

Mixed, incl. Fatty acid biosynthetic process, and Short-chain dehydrogenase/reductase SDR

6 of 37

1.61

2.15

2.66e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

4 of 9

2.05

2.3

2.02e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00550

Phosphopantetheine attachment site

4 of 9

2.05

2.15

4.60e-05

PF00501

AMP-binding enzyme

4 of 11

1.96

2.09

4.60e-05

PF00668

Condensation domain

3 of 3

2.4

2.03

0.00015

PF13193

AMP-binding enzyme C-terminal domain

3 of 6

2.1

1.71

0.00047

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

4 of 4

2.4

2.58

1.19e-05

IPR045851

AMP-binding enzyme, C-terminal domain superfamily

4 of 8

2.1

2.19

4.17e-05

IPR036736

ACP-like superfamily

4 of 9

2.05

2.17

4.17e-05

IPR009081

Phosphopantetheine binding ACP domain

4 of 9

2.05

2.17

4.17e-05

IPR000873

AMP-dependent synthetase/ligase domain

4 of 11

1.96

2.1

4.57e-05

(more ...)

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