STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1WI85Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (479 aa)    
Predicted Functional Partners:
A0A1Y1WJ60
Dihydrolipoyl dehydrogenase.
 0.999
A0A1Y1WN86
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
A0A1Y1WIV0
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.998
A0A1Y1W754
Thiamin diphosphate-binding protein.
 0.959
A0A1Y1WFU7
Dihydrolipoamide succinyltransferase.
  
0.959
A0A1Y1WBD5
Protein-serine/threonine kinase.
    
 0.951
A0A1Y1WK06
Citrate synthase; Belongs to the citrate synthase family.
  
 0.946
A0A1Y1WFG5
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.939
A0A1Y1WFR8
Glutathione-disulfide reductase.
 
 0.939
A0A1Y1W920
Oxoglutarate dehydrogenase, E1 component.
 
 0.936
Your Current Organism:
Linderina pennispora
NCBI taxonomy Id: 61395
Other names: ATCC 12442, CBS 312.51, L. pennispora, NRRL 2237
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