STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrAWith ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)    
Predicted Functional Partners:
emrB
Multidrug resistance protein B; Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
 
 0.996
AKE09099.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.934
mprA
DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.903
macB
Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.829
macB-2
Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.829
macB-3
Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.829
AKE11547.1
DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.776
AKE10291.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.711
AKE10416.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.696
mdtD
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.684
Your Current Organism:
Serratia liquefaciens
NCBI taxonomy Id: 614
Other names: ATCC 27592, Aerobacter liquefaciens, CCUG 9285, CIP 103238, DSM 4487, LMG 7884, LMG:7884, NCTC 12962, S. liquefaciens
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