STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKE09754.1Xylulose kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)    
Predicted Functional Partners:
deoR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.851
tas
Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.827
AKE09753.1
Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.777
AKE13066.1
Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
  
 0.692
xylA
Xylose isomerase; Catalyzes the interconversion of D-xylose to D-xylulose; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family.
 
  
 0.667
AKE09752.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.649
AKE08736.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.640
AKE12194.1
L-fucose mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.621
AKE09751.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.601
lsrK
Autoinducer kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
  
  
0.457
Your Current Organism:
Serratia liquefaciens
NCBI taxonomy Id: 614
Other names: ATCC 27592, Aerobacter liquefaciens, CCUG 9285, CIP 103238, DSM 4487, LMG 7884, LMG:7884, NCTC 12962, S. liquefaciens
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